BDBM223320 KDOAM-25

SMILES CCN(CCN(C)C)C(=O)CNCc1cc(ccn1)C(N)=O

InChI Key InChIKey=PNFMVADNCOGWME-UHFFFAOYSA-N

Data  37 IC50  1 Kd

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 223320   

TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223320(KDOAM-25)
Affinity DataIC50:  69nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223320(KDOAM-25)
Affinity DataIC50:  60nMAssay Description:We previously described 4-carboxy-2-triazolopyridines as selective KDM2 inhibitors (England et al., 2014). In efforts to find alternative scaffolds b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223320(KDOAM-25)
Affinity DataIC50:  27nMAssay Description:Inhibition of KDM5C (unknown origin) in presence of 4 uM 2-OGMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223320(KDOAM-25)
Affinity DataIC50:  558nMAssay Description:Inhibition of KDM5C (unknown origin) in presence of 300 uM 2-OGMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
University of Oxford

LigandPNGBDBM223320(KDOAM-25)
Affinity DataIC50:  69nMAssay Description:Inhibition of KDM5C (unknown origin ) by Alphascreen assayMore data for this Ligand-Target Pair
In DepthDetails PubMed